Endocrine Abstracts

IntroductionAcromegaly is a rare chronic disorder caused by GH hypersecretion. It’s associated with an elevated morbidity and mortality rate. Cardiovascular diseases’ complications are the first cause of mortality in patients. In this study we conducted an assessement of cardivascular risk factors in patients with acromegaly.Patients and methodsA retrospective evaluative study of 32 patients followe...

ObjectiveTo determine the clinical, biological and etiological aspects of hirsutism.MaterialA retrospective study from 2009 to 2017 included 51 patients explored and followed for hirsutism in the endocrinology department of the Rabta hospital.ResultsThe mean age of hirsute patients was 29 years, their average age of menarche was 12 years old. Hirsutism appeared be...

Patients with polycystic ovary syndrome (PCOS) have features of the metabolic syndrome, including insulin resistance, obesity, and dyslipidemia, suggesting an increased risk for cardiovascular disease.ObjectiveTo assess the prevalence of metabolic syndrome in patients with a polycystic ovarian sydrome (PCOS).MaterialWe conducted a retrospective study including 51 patients with secondary...

Introduction: The insulin tolerance test (ITT) is the gold standard for hypothalamic–pituitary adrenal axis assessment. There are different protocols depending on the number and timing of serum samples. Our study aimed to investigate the kinetics of serum glucose and cortisol levels during ITT and to determine the most appropriate times for blood samples.Methods: Our study was cross-sectional and descriptive. One hundred patients with suspected adre...

Introduction: Insulin resistance is classically a feature of type 2 diabetes mellitus (T2D). It may also develop among patients with type 1 diabetes (T1D) increasing the risk of cardiovascular mortality. Metabolic syndrome (MS) reflects a state of IR. The aim of this study was to assess the frequency of MS in a population of young adults with T1D and compare it to healthy controls.Methods: We conducted a case control study including 68 T1D patients and 6...

Introduction: Carotid intima-media thickness (CIMT) is a simple and non-invasive method used to detect atherosclerosis. This measure could predict future cardiovascular events. Some studies have showed an increased cardiovascular in non functional adrenal incidentalomas (NFAI). The aim of this case control study was to determine the relationship between NFAI and CIMT.Methods: This case control study included 40 NFAI patients (16 men, 24 women, mean age 5...

Background: Non functional adrenal incidentalomas (NFAI) constitute the majority of adrenal tumors. This entity is a result of advances in imaging techniques and their prevalent use in clinical practice. Among the associated metabolic effects of NFAI, dyslipidemia emerges as a key factor, stimulating growing interest in understanding the link between these two entities.Methods: This case control study included 40 NFAI patients (16 men, 24 women, mean age...

Introduction: Non-functioning adrenal incidentaloma (NFAI) is a frequently diagnosed since the increased use of radiological examinations. The recent studies have shown that NFAI might have negative cardiometabolic effects and increased cardiovascular risk. The aim of this case control study was to determine the relationship between NFAI, CRP-hs, uric acid and cardiovascular risk (CVR) based on GLOBORISK algorithm of Tunisia.Methods: This case-control st...

Introduction: Vitamin D deficiency is an emerging concern that has the potential to impact one’s health, even in sunny Mediterranean countries like Tunisia. This issue is particularly notable among indoor workers in the healthcare sector, who experience minimal sun exposure. The aim of this study was to describe the Vitamin D profile within this specific population and to establish its association with lipid parameters.Methods: This cross-sectional ...

Background: The diagnosis of adrenal incidentaloma (AI) is becoming more common with the rising use of radiological tests. Most of AI are nonfunctional adrenal incidentalomas (NFAI) that may produce small amounts of glucorcorticoids that, in consequence, may cause metabolic disorders. Metabolic syndrome being a significant health concern should be evaluated in patients with NFAI. The objective of the study was to assess metabolic syndrome (MS) prevalence and characteristics in...